Enterprise Library 3.0 comes with a new Visual Studio-Integrated Configuration Editor that allows you to graphically configure your app.config and web.config files within Visual Studio without having to switch back and forth between Visual Studio and the Stand-Alone Configuration Tool.
After you install Enterprise Library 3.0, you right-click on your app.config or web.config file to expose the context-sensitive menu that allows you the choice of opening the configuration file with the new configuration editor:

When using the Enterprise Library Configuration Editor to edit your app.config or web.config you get this cool design surface that allows you to graphically manage the application configuration. Included in the new version is the ability to manager AppSettings. There is also a new Environmental Overrides features that allows one to manage Test, Staging, Development, and Production Configuration Environments without all the manual synchronization that was done in the past.

Encryption and decryption of any configuration section ins included by the click of a simple drop-down menu in the Properties Area:

For more information on Enterprise Library 3.0, check out various Enterprise Library 3.0 Tutorials as well as download Enteprise Library 3.0.